Publications and Presentations

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Merrill et al - Suprachoroidal CLS-TA with and without Systemic Corticosteroid and/or Steroid-Sparing Therapy: A Post-Hoc Analysis of the Phase 3 PEACHTREE Clinical Trial
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Kansara et al - Evaluation of Long-Lasting Potential of Suprachoroidal Axitinib Suspension Via Ocular and Systemic Disposition in Rabbits
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Sharma et al - Safety of Suprachoroidal Injection Procedure Utilizing a Microinjector Across Three Retinal Disorders
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Shah et al - Post-Hoc Analysis of Suprachoroidal Injection Experience for Non-Infectious Uveitis
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Muya et al - Long-acting potential of suprachoroidally delivered BCX4161, a selective plasma kallikrein inhibitor, for diabetic macular edema
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Kansara et al - Suprachoroidally delivered non-viral DNA nanoparticles produce hMyo7A Protein in RPE-choroid in rabbits
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Ho et al - Suprachoroidal Injections Across Species via Multimodal Imaging
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Goldstein et al - Uveitic Macular Edema: OCT Anatomic and Temporal Biomarkers
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Fisher et al - Ophthalmic Procedure Training During COVID-19: Virtual and In-Person Training of the Suprachoroidal Injection Procedure
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Kuhrana et al - Extension study of the safety and efficacy of CLS-TA for treatment of macular oedema associated with non-infectious uveitis (MAGNOLIA)
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Henry et al - Suprachoroidal CLS-TA for non-infectious uveitis: an open-label, safety trial (AZALEA)
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Ciulla et al - Suprachoroidal Delivery of Small Molecules, Nanoparticles, Gene and Cell Therapies for Ocular Diseases
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Video - Brown - Axitinib: A Novel TKI Delivered by Suprachoroidal Injection for AMD, Clinical trial injection procedure after (dark orange) Betadine Ophthalmic Prep
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Presentation - Brown - Axitinib: A Novel TKI Delivered by Suprachoroidal Injection for AMD
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Suhler et al - Post Hoc Analysis of Suprachoroidal CLS-TA versus Rescue Therapies for Uveitic Macular Edema: Safety and Visual Function
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Grewal et al - OCT Anatomic and Temporal Biomarkers in Uveitic Macular Edema
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MacCumber et al - Suprachoroidal Administration of Small Molecule and Nanoparticle Suspensions: Pre-Clinical Results Correlate to Clinical Trial Outcomes
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Kurup et al - Safety of the Suprachoroidal Injection Procedure Utilizing SCS Microinjector® across Three Retinal Disorders
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Hariprasad et al - Multimodal Imaging of Suprachoroidal Injections: A Retina Surgeon’s Perspective
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Hancock et al - Biomechanics of suprachoroidal drug delivery: From benchtop to clinical investigation in ocular therapies
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Kansara, et al - Suprachoroidally Delivered DNA Nanoparticles Transfect Retina and Retinal Pigment Epithelium/Choroid in Rabbits
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Nguyen - Results from the Phase 3 PEACHTREE Clinical Trial Systemic Therapy and the Efficacy of CLS-TA: a Post-Hoc Analysis
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Bhisitkul et al - Suprachoroidal CLS-AX (axitinib injectable suspension) as a Potential Long-Acting Therapy for Neovascular Age-Related Macular Degeneration (nAMD)
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Wan et al – Clinical Characterization of Suprachoroidal Injection Procedure Utilizing a Microinjector across Three Retinal Disorders
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Suprachoroidal CLS-TA plus Intravitreal Aflibercept for Diabetic Macular Edema: A Randomized, Double-Masked, Parallel-Design, Controlled Study
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Ip - Correlation of Best Corrected Visual Acuity and Central Subfield Thickness in Macular Edema Due to Retinal Vein Occlusion, Diabetic Retinopathy and Uveitis
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Ciulla - Visual Acuity Outcomes and Anti-Vascular Endothelial Growth Factor Therapy Intensity in Macular Edema Due to Retinal Vein Occlusion: An Analysis of 12,214 Eyes
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Merrill - Results from the Phase 3 PEACHTREE Clinical Trial: Systemic Therapy and the Efficacy of CLS-TA, a Post-Hoc Analysis
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Holekamp - Suprachoroidally delivered non-viral DNA nanoparticles transfect chorioretinal cells in non-human primates and rabbits
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Kim - Suprachoroidal Delivery of Small Molecule Suspensions and Nanoparticles
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Henry - Post hoc Analysis of Clinical Suprachoroidal Injection Experience Across Indications
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Brown - Suprachoroidal CLS-AX (axitinib injectable suspension), as a Potential Long-Acting Therapy for Neovascular Age-Related Macular Degeneration (nAMD)
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Fisher - Suprachoroidal Delivery with the SCS Microinjector®: Characterization of Operational Forces
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Barakat et al - Post Hoc Analysis of Clinical Suprachoroidal Injection Experience Across Indications
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Muya et al - Pharmacokinetics and Ocular Tolerability of Suprachoroidal CLS-AX (axitinib injectable suspension)
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Kaiser et al - Suprachoroidal CLS-AX (axitinib injectable suspension), as a Potential Long-Acting Therapy for Neovascular Age-Related Macular Degeneration (nAMD)
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Grewal et al - Correlation of Best Corrected Visual Acuity and Central Subfield Thickness in Macular Edema Due to Retinal Vein Occlusion, Diabetic Retinopathy and Uveitis
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Henry et al - Results from the Phase 3 PEACHTREE Clinical Trial: Systemic Therapy and the Efficacy of CLS-TA, a Post-Hoc Analysis
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Henry et al - Post Hoc Analysis of Clinical Suprachoroidal Injection Experience Across Retinal Disease Indications
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Kurup et al - Post Hoc Analysis of Clinical Suprachoroidal Injection Experience for Non-infectious Uveitis
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Nguyen - Variations in Intraocular Pressure Following Administration of Suprachoroidal Triamcinolone Acetonide Suspension (CLS-TA) Results from the Phase 3 PEACHTREE Clinical Trial for Uveitic Macular Edema
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Reddy et al - Results from the Phase 3 PEACHTREE Clinical Trial: Systemic Therapy and the Efficacy of CLS-TA, a Post-Hoc Analysis
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Viral Kinsara - Suprachoroidal Delivery of Viral and Nonviral Gene Therapy for Retinal Diseases
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Yeh et al - Efficacy and Safety of Suprachoroidal CLS-TA for Macular Edema Secondary to Noninfectious Uveitis: Phase 3, Randomized Trial
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Kurup - Suprachoroidal CLS-AX (axitinib injectable suspension), as a Potential Long-Acting Therapy for Neovascular Age-Related Macular Degeneration (nAMD)
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Ip - Suprachoroidal CLS-TA Plus Aflibercept Compared with Aflibercept Monotherapy for DME: Analysis of OCT Biomarkers in the Randomized Phase 2 TYBEE Trial
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Singer - IOP Following Administration of Suprachoroidal Triamcinolone Acetonide Suspension (CLS-TA): Results from the Phase 3 PEACHTREE Clinical Trial for Uveitis
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MacCumber - Suprachoroidal Delivery for Ocular Gene Therapy: Nonclinical Experiments Evaluating Non-Viral DNA Nanoparticles in Non-Human Primates
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Albini - Update on Therapeutic Suprachoroidal Injections
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Yeh - Front-line Local Therapies for Uveitis: From Clinical Trials to Practice
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Stephen Yeh - Suprachoroidal Injection of Triamcinolone Acetonide, CLS-TA, for Macular Edema Due to Noninjectious Uveitis: A Randomized, Phase 2 Study (DOGWOOD)
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Jae Hwan Jung - Collagenase injection into the suprachoroidal space of the eye to expand drug delivery coverage and increase posterior drug targeting
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Jae Hwan Jung - Targeting drug delivery within the suprachoroidal space
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Habot-Wilner - Suprachoroidally injected pharmacological agents for the treatment of chorio‐retinal diseases: a targeted approach
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Levison - A Subgroup Analysis of Subjects Diagnosed with Anterior Uveitis from the Phase 3 PEACHTREE Clinical Trial
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Ip - Suprachoroidal CLS-TA Plus Aflibercept Compared with Aflibercept Monotherapy for DME: Selected Secondary Results of the Randomized Phase 2 TYBEE Trial
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Yeh - Suprachoroidal Triamcinolone Acetonide Suspension (CLS-TA) and Intraocular Pressure: Results from the Phase 3 PEACHTREE Clinical Trial for Uveitis
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Kay - Suprachoroidal delivery for ocular gene therapy: nonclinical experiments evaluating non-viral DNA nanoparticles.
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Merrill – Suprachoroidal Triamcinolone Acetonide Suspension (CLS-TA) and Intraocular Pressure: Results from the Phase 3 PEACHTREE Clinical Trial for Uveitis
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Sharma - Suprachoroidal CLS-TA Maintains Efficacy Outcomes Through 48-weeks in Uveitic Macular Edema subjects: Results of the MAGNOLIA Phase 3 Extension Study
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Neumann – Suprachoroidal CLS-TA Improves Patient Outcomes in Uveitis of All Anatomic Subtypes: Results of the Phase 3 PEACHTREE Study
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Ip - Suprachoroidal CLS-TA Plus Aflibercept Compared with Aflibercept Monotherapy for DME: Primary and Selected Secondary Results of the Randomized Phase 2 TYBEE Trial
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Henry - Suprachoroidal CLS-TA Improves Patient Outcomes in Uveitis of All Anatomic Subtypes: Results of the Phase 3 PEACHTREE Study
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Merrill - Suprachoroidally Injected CLS-TA in Uveitis Maintains Efficacy Outcomes Through 48 Weeks: Results of the MAGNOLIA Phase 3 Extension Study
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Henry - Treatment response analysis of visual acuity and central subfield retinal thickness following suprachoroidal CLS-TA
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Suhler - Suprachoroidal Administration of Triamcinolone Acetonide (CLS-TA) for the treatment of Macular Edema in Noninfectious Uveitis: Pooled Results of Three Clinical Trials
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Yeh - Suprachoroidal CLS-TA Improves Visual Acuity and Macular Edema in Noninfectious Uveitis: Results of the Phase 3 PEACHTREE Study
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Video Presentation - Suprachoridial administration of DNA nanoparticles transfect chorioretinal cells in primates and rabbits
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Hariprasad - Suprachoroidally Injected CLS-TA Results in Rapid and Sustained Resolution of Macular Edema in a Majority of Patients
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Henry - Suprachoroidal Delivery of CLS-TA for Uveitic Macular Edema: Results of the Phase 3 PEACHTREE Trial
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Kansara - Suprachoroidally delivered non-viral DNA nanoparticles transfect chorioretinal cells in non-human primates and rabbits
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Kiss - A Novel Approach to Ocular Gene Therapy: Evaluation of Suprachoroidally Administered Non-Viral DNA Nanoparticles in Rabbits
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Merrill - Suprachoroidal CLS-TA Maintains Efficacy Outcomes Through 48-weeks in Uveitic Macular Edema subjects: Results of the MAGNOLIA Phase 3 Extension Study
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Shah - Clinical Experience with the SCS Microinjector™ for Suprachoroidal Injections by Ophthalmologists
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Wykoff - Suprachoroidal CLS-TA Plus Aflibercept Compared to Aflibercept Monotherapy for DME: Results of the Randomized Phase 2 TYBEE Trial
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Charles C. Wykoff - Suprachoroidal Triamcinolone for Diabetic Macular Edema: The HULK Trial
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Yeh, S. - Suprachoroidally Injected CLS-TA Improves Visual Acuity and Macular Edema in Noninfectious Uveities Results of the Phase 3 PEACHTREE Study
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Bryce Chiang - The suprachoroidal space as a route of administration to the posterior segment of the eye
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Alex S. Willoughby - Choroidal Changes After Suprachoroidal Injection of Triamcinolone Acetonide in Eyes With Macular Edema Secondary to Retinal Vein Occlusion
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Peter A. Campochiaro - Suprachoroidal Triamcinolone Acetonide for Retinal Vein Occlusion: Results of the Tanzanite Study
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Shaun I. R. Lampen - Suprachoroidal Space Alterations Following Delivery of Triamcinolone Acetonide: Post-Hoc Analysis of the Phase 1/2 HULK Study of Patients With Diabetic Macular Edema
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Taraborelli, D., Noronha, G., Yoo, J., Laird, O., Cooper, M. - A One-week Study to Evaluate Safety, Tolerability, and Retinal Cell Transfection of Non-viral DNA Nanoparticles Administered by Suprachoroidal Injection
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Patel SR, Berezovsky D, McCarey BE, Nickerson JM, Edelhauser HF, Prausnitz MR. - Intraocular Pharmacokinetics of Suprachoroidal Drug Delivery Administered Using Hollow Microneedles.
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Patel SR, Verhoeven RS, Burke B, Viaud K, Edelhauser HF. Safety and Tolerability of Drugs Within the Suprachoroidal Space in Albino Rabbits. ARVO Meeting Abstracts 2014; 4886-C0082.
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Kissner J, Patel S, Prusakiewicz J, Alton D, Bikzhanova G, Geisler L, Burke B, Noronha G. Pharmacokinetics Including Ocular Distribution Characteristics of Suprachoidally Administered CLS011A in Rabbits Could be Beneficial for a Wet AMD Therapeutic Candi
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Burke, B. - Targeted delivery of Triamcinolone Acetonide and CLS011A To the posterior ocular tissues via Suprachoroidal administration
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Shah, M. - Development and clinical experience with Suprachoroidal injection of Triamcinolone acetonide (CLS-TA) as a local treatment for noninfectious uveitis
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Campochiaro, P., Wykoff, C., Brown, C. - Suprachoroidal Triamcinolone Acetonide for Retinal Vein Occlusion: Results of the Tanzanite Study
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Hariprasad, S. - Patient Safety Data Across Clinical Trials Using Suprachoroidal Injection of Triamcinolone Acetonide
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Michael Singer, MD - Tanzanite Phase 2 Retinal vein occlusion (RVO) trial
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Wang, R. - The potential for treatment of noninfectious uveitis using a suprachoroidal approach
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Wykoff C. Durability of Suprachoroidal Triamcinolone Acetonide in Combination with Aflibercept in the Management of Retinal Vein Occlusion: 9-Month Analysis of the TANZANITE Phase 2 Trial and Extension Study
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Wykoff, C., Khurana, R. - Suprachoroidal Triamcinolone Acetonide with & without Intravitreal Aflibercept for DME: Results of the 6 Month Prospective Phase 1/2 Hulk trial
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Yoo, J - Characterization of the dynamics of liquid and gel spread in the Suprachoroidal space of enucleated porcine eyes
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Goldstein D, Do D, Noronha G, Kissner J, Srivastava S, Nguyen Q. - Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis
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Yeh S. - Suprachoroidal Administration of Triamcinolone Acetonide: Results of a Phase 2 Study of Patients with Noninfectious Uveitis
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Do D. - Clinical Trial Results From Patients With Macular Edema Due to Noninfectious Uveitis Treated With 4.0 mg of Triamcinolone Acetonide Using a Suprachoroidal Injection
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Debra A. Goldstein - Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis
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Ela Moisseiev - The suprachoroidal space: from potential space to a space with potential
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Samirkumar R. Patel - Targeted Drug Delivery Within the Eye Through the Suprachoroidal Space
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Brown D. Suprachoroidal Triamcinolone Acetonidewith Intravitreal Aflibercept For Retinal Vein Occlusion: Phase 2 Results –TANZANITE study
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Fisher, N., Yoo, J., Hancock, S., Andino, R. - A Novel Technique to Characterize Key Fluid Mechanic Properties of the Suprachoroidal Injection Procedure in an In Vivo Model
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Hariprasad S. - Suprachoroidal Administration of Triamcinolone Acetonide: Combined Results of Phase 1/2 and Phase 2 Clinical Studies
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Kurup S. - Suprachoroidal Drug Administration
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Patel S, Kissner J, Zarnitsyn V, Farjo R, Noronha G. - Efficacy of Suprachoroidal Aflibercept in a Laser Induced Choroidal Neovascularization Model.
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Taraborelli D, Burke B, Noronha G. Ocular Tolerability and Toxicokinetics of Suprachoroidally Administered CLS-TA, Triamcinolone Acetonide Injectable Suspension, in Combination with Intravitreal Eylea® in Rabbits. ARVO Meeting Abstracts 2016; 296-B0329.
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Zarnitsyn V, Patel S, Yoo J, Noronha G. - Characterization of Suprachoroidal Injection in Multiple Species.
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Wet AMD Kissner J, Patel S, Prusakiewicz J, Alton D, Bikzhanova G, Geisler L, Burke B, Noronha G. – Pharmacokinetics Including Ocular Distribution Characteristics of Suprachoroidally Administered CLS011A in Rabbits Could be Beneficial for a Wet AMD...
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Wet AMD Morales-Canton V, Fromow-Guerra J, Longoria S, Vera R, Widmann M, Patel S, Yerxa B. – Suprachoroidal Microinjection of Bevacizumab is Well Tolerated in Human Patients
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Uma Do J.P. Rai - The suprachoroidal pathway: a new drug delivery route to the back of the eye
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Andino RV, Allen EV, Patel SR, Edelhauser HF, Yoo JI. - Intraocular Pressure Changes Resulting from Suprachoroidal and Intravitreal Injections in Ex-Vivo Porcine Eyes.
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Edelhauser HF, Verhoeven RS, Burke B, Struble CB, Patel SR. - Intraocular Distribution and Targeting of Triamcinolone Acetonide Suspension Administered into the Suprachoroidal Space.
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Noronha G, Edelhauser HF, Patel SR, Burke B, Verhoeven RS. Safety and Toxicokinetics of Suprachoroidal Space Injections of Triamcinolone Acetonide Suspension in Albino Rabbits. ARVO Meeting Abstracts 2014; 4887-C0083.
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Yoo JI, A32c03ndino RV, Zarnitsyn V, Strudthoff K, Patel SR, Edelhauser HF. - Ultrasound Biomicrocopy to Visualize Suprachoroidal Injections of Enucleated Human Eyes.
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Zarnitsyn V, Patel SR, Verhoeven RS, Lawrence MS. - Characterization of Sodium Fluorescein Administered into the Suprachoroidal Space of Nonhuman Primates Using a Microneedle.
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Morales-Canton V, Fromow-Guerra J, Longoria S, Vera R, Widmann M, Patel S, Yerxa B. Suprachoroidal Microinjection of Bevacizumab is Well Torerated in Human Patients. ARVO Meeting Abstracts 2013;3299-A0150.
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Burke B, Verhoeven R, Patel S. - Comparison of the Total Amount of Triamcinolone Acetonide Delivered Via Suprachoroidal or Intravitreal Administration.
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Edelhauser H, Patel S, Meschter C, Dean R, Powell K, Verhoeven R. - Suprachoroidal Microinjection Delivers Triamcinolone Acetonide to Therapeutically-Relevant Posterior Ocular Structures and Limits Exposure in the Anterior Segment. ARVO Meeting Abstracts
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Gilger B, Abarca E, Salmon J, Patel S. - Treatment of Acute Posterior Uveitis by Injection of Triamcinolone Acetonide into the Suprachoroidal Space Using Microneedles.
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Patel S, Carvalho R, Mundwiler K, Meschter C, Verhoeven R. - Evaluation of Suprachoroidal Microinjection of Triamcinolone Acetonide in a Model of Panuveitis in Albino Rabbits.
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Verhoeven R, Patel S, Viaud-Quentric K, Cacciamani F, Amar T, Yerxa B. - Suprachoroidal Microinjection of Triamcinolone Acetonide is Well Tolerated in the Albino Rabbit.
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Smirkumar R. Patel - Targeted Administration into the Suprachoroidal Space Using a Microneedle for Drug Delivery to the Posterior Segment of the Eye
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Berezovsky DE, Patel SR, Grossniklaus HE, Edelhauser HF. - Microneedle-Based Suprachoroidal Injections in Rabbits: Histological Study Using Triamcinolone Acetonide. ARVO Meeting Abstracts 2012;53:486.
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Mansoor S, Patel SR, Tas C, et al. - Pharmacokinetics and Biodistribution of Bevacizumab Following Suprachoroidal Injection into the Rabbit Eye Using a Microneedle.
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Patel SR, Powers E, Prausnitz MR, Edelhauser HF. - Fluid Infusion Into the Corneal Stroma Using a Microneedle.
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Patel SR. - Microneedle Enabled Tissue Targeted Drug Delivery for the Anterior and Posterior Segment of the Eye.
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Gabriela S. Seiler - Effect and Distribution of Contrast Medium after Injection into the Anterior Suprachoroidal Space in Ex Vivo Eyes
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Berezovsky DE, Patel SR, McCarey BE, Grossniklaus HE, Prausnitz MR, Edelhauser HF. In Vivo Evaluation of Fluorescent Microparticles Injected in the Rabbit Suprachoroidal Space Using Hollow Microneedles. ARVO Meeting Abstracts 2011;52:2058.
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Kang SJ, Patel SR, Berezovsky DE, Zhang Q, Yang H, Grossniklaus HE. - Suprachoroidal Injection of Microspheres with Microcatheter in a Rabbit Model of Uveal Melanoma.
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Patel SR, Bergman L, Berglin LC, et al. - Surface Area Coverage of Suprachoroidal Injections Using A Hollow Microneedle in Fresh Human Globes.
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Patel SR. - Targeted Drug Delivery to the Suprachoroidal Space: A Minimally Invasive Approach toTreating Chorioretinal Diseases Using Microneedles.
Patel SR. - Targeting to the Suprachoroidal Space of the Eye Using a Hollow Microneedle.
Berglin LC, Bergman L, Patel SR, et al. - Tracing of Suprachoroidally Microneedle Injected Labeled Drugs and Microbeads in Human, Pig and Rabbit Tissue Using Liquid Nitrogen Snap-Freeze Thaw and Lypholization Techniques.
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Patel S, Edelhauser HF, Nickerson JM, Prausnitz MR. - Suprachoroidal Drug Delivery Using Microneedles.
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Prausnitz MR, Jiang J, Patel SR, et al. - Ocular Drug Delivery Using Microneedles.
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As a courtesy to our stakeholders, Clearside Biomedical, Inc. lists posters and presentations delivered on, or related to our programs at various medical meetings and in various publications. Some of these materials may be authored by individuals outside the Company with or without funding from Clearside. Please note that the studies, data, opinions, and other disclosures made by these individuals may not fully reflect the status of the Clearside programs. Clearside Biomedical does not by its reference above or distribution necessarily imply its endorsement of or concurrence with such information, conclusions, or recommendations.