CLEARSIDE DEVELOPED PROGRAMS

THERAPEUTIC

TYPE

INDICATION

CURRENT STATUS / PARTNER

THERAPEUTIC, TYPE, INDICATION, STATUS, PARTNER

Tyrosine Kinase Inhibitor

Wet AMD

Corticosteroid (Triamcinolone Acetonide)

Uveitic Macular Edema1
(U.S. & Canada)

XIPERE® / ARCATUS

Corticosteroid (Triamcinolone Acetonide)

Uveitic Macular Edema2
(Asia Pacific ex-Japan)

XIPERE® / ARCATUS

Corticosteroid (Triamcinolone Acetonide)

Diabetic Macular Edema2
(Asia Pacific ex-Japan)

SCS Microinjector® Partner Clinical Development Programs

THERAPEUTIC

TYPE

INDICATION

CURRENT STATUS / PARTNER

THERAPEUTIC, TYPE, INDICATION, STATUS, PARTNER

Bel-Sar

Viral-like Drug Conjugate

Choroidal Melanoma

ABBV-RGX-314

AAV Gene Therapy

Diabetic Retinopathy

ABBV-RGX-314

AAV Gene Therapy

Wet AMD

Avoralstat

Plasma Kallikrein Inhibitor

Diabetic Macular Edema

Footnotes:

1XIPERE® (triamcinolone acetonide injectable suspension), for suprachoroidal use has received U.S. FDA Approval and is being commercialized by Bausch + Lomb.

2In China, Arctic Vision is responsible for clinical development of ARCATUS™ (triamcinolone acetonide injectable suspension), formerly referred to as ARVN001, and known as XIPERE® in the U.S.