Diabetic Macular Edema (DME) is an accumulation of fluid in the macula caused by leaky blood vessels as a consequence of diabetes mellitus. It is defined as retinal thickening within 2 disc diameters of the macula center. DME is the most common complication of Diabetes in patients with Diabetic Retinopathy (DR). DR affects more than 150 million people worldwide.1 It may cause images to appear blurry or wavy and colors that seem “washed out”.
1. Gupta N, Mansoor S, Sharma A, et al. Diabetic retinopathy and VEGF. Open Ophthalmol J. 2013;7:4-10.
Combination arm: Intravitreal Eylea suprachoroidal CLS-TA (n=36)
Any additional treatment based on as needed criteria at Week 16 and Week 20 will be intravitreal Eylea