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Uveitis eye

Uveitis
(Macular Edema associated with Uveitis)

  • Uveitis is a collection of inflammatory conditions affecting the eye. Roughly 30 diseases causing inflammation in the eye fall under the classification of Uveitis.
  • Uveitis is further identified by the dominant (anatomic) location of the inflammation in the eye as anterior, intermediate, posterior, or pan uveitis.
  • Over 350,000 adults in the U.S. have uveitis. Most patients are aged 20-50 years. 2
  • Macular edema may be found with any geographic location of uveitis.3 Approximately 30-40% of uveitis patients have macular edema.4.
  • There are no approved treatments for macular edema secondary to uveitis.

1. Miserocchi, E., Fogliato, G., Modorati, G. & Bandello, F. Review on the worldwide epidemiology of uveitis. European Journal of Ophthalmology 2013;23:705-717.

2. Thorne, J. E., Suhler, E., Skup, M., Tari, S., Macaulay, D., Chao, J., & Ganguli, A. Prevalence of noninfectious uveitis in the United States: A claims-based analysis. JAMA Ophthalmology 2016;134, 1237–1245.

3. Karim, R., Sykakis, E., Lightman, S. & Fraser-Bell, S. Interventions for the treatment of uveitic macular edema: a systematic review and meta-analysis. Clinical ophthalmology (Auckland, N.Z.) 2013;7, 1109–44.

4. Lardenoye, C. W. T. A., van Kooij, B. & Rothova, A. Impact of Macular Edema on Visual Acuity in Uveitis. Ophthalmology 2006;113, 1446–1449.

Diabetic Macular Edema (DME)

Diabetic Macular Edema (DME) is an accumulation of fluid in the macula caused by leaky blood vessels as a consequence of diabetes mellitus. It is defined as retinal thickening within 2 disc diameters of the macula center. DME is the most common complication of Diabetes in patients with Diabetic Retinopathy (DR). DR affects more than 150 million people worldwide.1 It may cause images to appear blurry or wavy and colors that seem “washed out”.

1. Gupta N, Mansoor S, Sharma A, et al. Diabetic retinopathy and VEGF. Open Ophthalmol J. 2013;7:4-10.

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